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Systematic name YKL194C
Gene name MST1
Feature type ORF, Verified
Coordinates Chr XI:78646..77258
Primary SGDID S000001677

Description of YKL194C: Mitochondrial threonyl-tRNA synthetase; aminoacylates both the canonical threonine tRNA tT(UGU)Q1 and the unusual threonine tRNA tT(XXX)Q2 in vitro[1][2][3][4]


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  1. Ling J, et al. (2012) Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment. Proc Natl Acad Sci U S A () SGD PMID 22343532
  2. Pape LK and Tzagoloff A (1985) Cloning and characterization of the gene for the yeast cytoplasmic threonyl-tRNA synthetase. Nucleic Acids Res 13(17):6171-83 SGD PMID 2995918
  3. Pape LK, et al. (1985) Characterization of a yeast nuclear gene (MST1) coding for the mitochondrial threonyl-tRNA1 synthetase. J Biol Chem 260(28):15362-70 SGD PMID 2999113
  4. Su D, et al. (2011) An unusual tRNAThr derived from tRNAHis reassigns in yeast mitochondria the CUN codons to threonine. Nucleic Acids Res () SGD PMID 21321019

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