YKL101W

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Systematic name YKL101W
Gene name HSL1
Aliases ELM2, NIK1
Feature type ORF, Verified
Coordinates Chr XI:248920..253476
Primary SGDID S000001584


Description of YKL101W: Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates with the assembled septin filament; required along with Hsl7p for bud neck recruitment, phosphorylation, and degradation of Swe1p[1][2][3][4][5]




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References

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  1. Barral Y, et al. (1999) Nim1-related kinases coordinate cell cycle progression with the organization of the peripheral cytoskeleton in yeast. Genes Dev 13(2):176-87 SGD PMID 9925642
  2. Longtine MS, et al. (2000) Septin-dependent assembly of a cell cycle-regulatory module in Saccharomyces cerevisiae. Mol Cell Biol 20(11):4049-61 SGD PMID 10805747
  3. McMillan JN, et al. (1999) The morphogenesis checkpoint in Saccharomyces cerevisiae: cell cycle control of Swe1p degradation by Hsl1p and Hsl7p. Mol Cell Biol 19(10):6929-39 SGD PMID 10490630
  4. Sakchaisri K, et al. (2004) Coupling morphogenesis to mitotic entry. Proc Natl Acad Sci U S A 101(12):4124-9 SGD PMID 15037762
  5. Shulewitz MJ, et al. (1999) Hsl7 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 19(10):7123-37 SGD PMID 10490648

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