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Systematic name YKL080W
Gene name VMA5
Aliases CSL5, VAT3
Feature type ORF, Verified
Coordinates Chr XI:285030..286208
Primary SGDID S000001563

Description of YKL080W: Subunit C of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane[1][2]


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  1. Beltran C, et al. (1992) Cloning and mutational analysis of the gene encoding subunit C of yeast vacuolar H(+)-ATPase. J Biol Chem 267(2):774-9 SGD PMID 1730668
  2. Ho MN, et al. (1993) Isolation of vacuolar membrane H(+)-ATPase-deficient yeast mutants; the VMA5 and VMA4 genes are essential for assembly and activity of the vacuolar H(+)-ATPase. J Biol Chem 268(1):221-7 SGD PMID 8416931

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