YKL073W

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Systematic name YKL073W
Gene name LHS1
Aliases CER1, SSI1
Feature type ORF, Verified
Coordinates Chr XI:296430..299075
Primary SGDID S000001556


Description of YKL073W: Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway[1][2][3][4]




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References

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  1. Baxter BK, et al. (1996) SSI1 encodes a novel Hsp70 of the Saccharomyces cerevisiae endoplasmic reticulum. Mol Cell Biol 16(11):6444-56 SGD PMID 8887673
  2. Craven RA, et al. (1996) A novel Hsp70 of the yeast ER lumen is required for the efficient translocation of a number of protein precursors. EMBO J 15(11):2640-50 SGD PMID 8654361
  3. Hamilton TG and Flynn GC (1996) Cer1p, a novel Hsp70-related protein required for posttranslational endoplasmic reticulum translocation in yeast. J Biol Chem 271(48):30610-3 SGD PMID 8940034
  4. Steel GJ, et al. (2004) Coordinated activation of Hsp70 chaperones. Science 303(5654):98-101 SGD PMID 14704430

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