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Systematic name YKL048C
Gene name ELM1
Aliases LDB9
Feature type ORF, Verified
Coordinates Chr XI:349136..347214
Primary SGDID S000001531

Description of YKL048C: Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis; required for the regulation of other kinases; forms part of the bud neck ring[1][2][3][4][5]


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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [6] [7]



See Help:References on how to add references

  1. Bouquin N, et al. (2000) Regulation of cytokinesis by the Elm1 protein kinase in Saccharomyces cerevisiae. J Cell Sci 113 ( Pt 8)():1435-45 SGD PMID 10725226
  2. Garrett JM (1997) The control of morphogenesis in Saccharomyces cerevisiae by Elm1 kinase is responsive to RAS/cAMP pathway activity and tryptophan availability. Mol Microbiol 26(4):809-20 SGD PMID 9427410
  3. Koehler CM and Myers AM (1997) Serine-threonine protein kinase activity of Elm1p, a regulator of morphologic differentiation in Saccharomyces cerevisiae. FEBS Lett 408(1):109-14 SGD PMID 9180279
  4. Sreenivasan A and Kellogg D (1999) The elm1 kinase functions in a mitotic signaling network in budding yeast. Mol Cell Biol 19(12):7983-94 SGD PMID 10567524
  5. Thomas CL, et al. (2003) Assembly interdependence among the S. cerevisiae bud neck ring proteins Elm1p, Hsl1p and Cdc12p. Yeast 20(9):813-26 SGD PMID 12845607
  6. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  7. submitted by Jeff Ubersax on 2004-01-27

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