YKL014C

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Systematic name YKL014C
Gene name URB1
Aliases NPA1
Feature type ORF, Verified
Coordinates Chr XI:416913..411619
Primary SGDID S000001497


Description of YKL014C: Nucleolar protein required for the normal accumulation of 25S and 5.8S rRNAs, associated with the 27SA2 pre-ribosomal particle; proposed to be involved in the biogenesis of the 60S ribosomal subunit[1][2][3]




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References

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  1. Dez C, et al. (2004) Npa1p, a component of very early pre-60S ribosomal particles, associates with a subset of small nucleolar RNPs required for peptidyl transferase center modification. Mol Cell Biol 24(14):6324-37 SGD PMID 15226434
  2. Mnaimneh S, et al. (2004) Exploration of essential gene functions via titratable promoter alleles. Cell 118(1):31-44 SGD PMID 15242642
  3. Rosado IV and de la Cruz J (2004) Npa1p is an essential trans-acting factor required for an early step in the assembly of 60S ribosomal subunits in Saccharomyces cerevisiae. RNA 10(7):1073-83 SGD PMID 15208443

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