YJR021C

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Systematic name YJR021C
Gene name REC107
Aliases MER2
Feature type ORF, Verified
Coordinates Chr X:469579..468555
Primary SGDID S000003782


Description of YJR021C: Protein involved in early stages of meiotic recombination; involved in coordination between the initiation of recombination and the first division of meiosis; part of a complex (Rec107p-Mei4p-Rec114p) required for ds break formation[1][2][3][4]




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Community Commentary

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Interactions

Two Hybrid

Two Hybrid interaction with Mei4, Xrs2
[5] [6]


Two Hybrid interaction with Rec114
Meiosis-specific two hybrid interaction [5] [6]


Two Hybrid interaction with Rec114
Meiosis-specific two hybrid interaction [5] [6]


Two Hybrid interaction with Rec114
Meiosis-specific two hybrid interaction [5] [6]





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References

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  1. Li J, et al. (2006) Saccharomyces cerevisiae Mer2, Mei4 and Rec114 form a complex required for meiotic double-strand break formation. Genetics 173(4):1969-81 SGD PMID 16783010
  2. Malone RE, et al. (1991) Isolation of mutants defective in early steps of meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics 128(1):79-88 SGD PMID 2060778
  3. Malone RE, et al. (2004) The signal from the initiation of meiotic recombination to the first division of meiosis. Eukaryot Cell 3(3):598-609 SGD PMID 15189982
  4. Ohta K, et al. (1998) Mutations in the MRE11, RAD50, XRS2, and MRE2 genes alter chromatin configuration at meiotic DNA double-stranded break sites in premeiotic and meiotic cells. Proc Natl Acad Sci U S A 95(2):646-51 SGD PMID 9435246
  5. 5.0 5.1 5.2 5.3 Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 SGD PMID 14992724
  6. 6.0 6.1 6.2 6.3 submitted by Scott Keeney on 2004-05-02

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