YJL189W

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Systematic name YJL189W
Gene name RPL39
Aliases PUB2, RPL46, SPB2
Feature type ORF, Verified
Coordinates Chr X:75933..76474
Primary SGDID S000003725


Description of YJL189W: Protein component of the large (60S) ribosomal subunit, has similarity to rat L39 ribosomal protein; required for ribosome biogenesis; loss of both Rpl31p and Rpl39p confers lethality; also exhibits genetic interactions with SIS1 and PAB1[1][2][3][4][5]




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References

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  1. Horton LE, et al. (2001) The yeast hsp70 homologue Ssa is required for translation and interacts with Sis1 and Pab1 on translating ribosomes. J Biol Chem 276(17):14426-33 SGD PMID 11279042
  2. Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90 SGD PMID 12490706
  3. Peisker K, et al. (2008) Ribosome-associated complex binds to ribosomes in close proximity of Rpl31 at the exit of the polypeptide tunnel in yeast. Mol Biol Cell 19(12):5279-88 SGD PMID 18829863
  4. Planta RJ and Mager WH (1998) The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Yeast 14(5):471-7 SGD PMID 9559554
  5. Sachs AB and Davis RW (1990) Translation initiation and ribosomal biogenesis: involvement of a putative rRNA helicase and RPL46. Science 247(4946):1077-9 SGD PMID 2408148

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