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Systematic name YJL093C
Gene name TOK1
Aliases DUK1, YKC1, YORK, YPK1
Feature type ORF, Verified
Coordinates Chr X:256812..254737
Primary SGDID S000003629

Description of YJL093C: Outward-rectifier potassium channel of the plasma membrane with two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin[1][2][3][4]


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  1. Ahmed A, et al. (1999) A molecular target for viral killer toxin: TOK1 potassium channels. Cell 99(3):283-91 SGD PMID 10555144
  2. Ketchum KA, et al. (1995) A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem. Nature 376(6542):690-5 SGD PMID 7651518
  3. Loukin SH and Saimi Y (2002) Carboxyl tail prevents yeast K(+) channel closure: proposal of an integrated model of TOK1 gating. Biophys J 82(2):781-92 SGD PMID 11806920
  4. Saldana C, et al. (2002) Splitting the two pore domains from TOK1 results in two cationic channels with novel functional properties. J Biol Chem 277(7):4797-805 SGD PMID 11714706

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