YJL083W

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Systematic name YJL083W
Gene name TAX4
Aliases
Feature type ORF, Verified
Coordinates Chr X:278841..280655
Primary SGDID S000003619


Description of YJL083W: EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS[1][2][3]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. [4] [5]





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References

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  1. Bugnicourt A, et al. (2008) Irs4p and Tax4p: two redundant EH domain proteins involved in autophagy. Traffic 9(5):755-69 SGD PMID 18298591
  2. Morales-Johansson H, et al. (2004) Negative regulation of phosphatidylinositol 4,5-bisphosphate levels by the INP51-associated proteins TAX4 and IRS4. J Biol Chem 279(38):39604-10 SGD PMID 15265867
  3. Paoluzi S, et al. (1998) Recognition specificity of individual EH domains of mammals and yeast. EMBO J 17(22):6541-50 SGD PMID 9822599
  4. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  5. submitted by Viktor Boer on 2003-07-25

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