YJL053W

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Systematic name YJL053W
Gene name PEP8
Aliases GRD6, VPS26, VPT4
Feature type ORF, Verified
Coordinates Chr X:335898..337037
Primary SGDID S000003589


Description of YJL053W: Vacuolar protein sorting protein that forms part of the multimeric membrane-associated retromer complex along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport; interacts with Ypt7p[1][2][3]




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References

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  1. Edgar AJ and Polak JM (2000) Human homologues of yeast vacuolar protein sorting 29 and 35. Biochem Biophys Res Commun 277(3):622-30 SGD PMID 11062004
  2. Liu TT, et al. (2012) Rab GTPase regulation of retromer-mediated cargo export during endosome maturation. Mol Biol Cell 23(13):2505-15 SGD PMID 22593205
  3. Seaman MN, et al. (1998) A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J Cell Biol 142(3):665-81 SGD PMID 9700157

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