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Systematic name YIL170W
Gene name HXT12
Feature type pseudogene
Coordinates Chr IX:19847..21220
Primary SGDID S000001432

Description of YIL170W: Possible pseudogene in strain S288C; YIL170W/HXT12 and the adjacent ORF, YIL171W, together encode a non-functional member of the hexose transporter family[1][2][3][4]


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Alleles, Strains, and Phenotypes

Multiple Knockout Strains

Strain Background: CEN.PK2-1C
Genotype: EBY4000 (hxt)
Together with: HXT15, MPH2, HXT7, HXT6, HXT3, HXT13, HXT10, MAL11, HXT4, HXT1, HXT5, HXT8, HXT9, HXT16, MPH3, GAL2, HXT2, HXT14, HXT17, HXT11
Phenotype(s): Viable , Conditionally inviable when on glucose medium

The complete hxt null strain (EBY4000) is unable to take up hexoses and to grow on them. It is well suited to express and characterize heterologous glucose transporters. [4] [5]



See Help:References on how to add references

  1. Andre B (1995) An overview of membrane transport proteins in Saccharomyces cerevisiae. Yeast 11(16):1575-611 SGD PMID 8720066
  2. Kruckeberg AL (1996) The hexose transporter family of Saccharomyces cerevisiae. Arch Microbiol 166(5):283-92 SGD PMID 8929273
  3. Nelissen B, et al. (1995) Phylogenetic classification of the major superfamily of membrane transport facilitators, as deduced from yeast genome sequencing. FEBS Lett 377(2):232-6 SGD PMID 8543057
  4. 4.0 4.1 Wieczorke R, et al. (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8 SGD PMID 10618490 Cite error: Invalid <ref> tag; name "S000056317" defined multiple times with different content
  5. submitted by Eckhard Boles on 2003-03-17

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