YIL170W
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| Systematic name | YIL170W |
| Gene name | HXT12 |
| Aliases | |
| Feature type | pseudogene |
| Coordinates | Chr IX:19847..21220 |
| Primary SGDID | S000001432 |
Description of YIL170W: Possible pseudogene in strain S288C; YIL170W/HXT12 and the adjacent ORF, YIL171W, together encode a non-functional member of the hexose transporter family[1][2][3][4]
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Contents
Community Commentary
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Alleles, Strains, and Phenotypes
Multiple Knockout Strains
Strain Background: CEN.PK2-1C
Genotype: EBY4000 (hxt)
Together with: HXT15, MPH2, HXT7, HXT6, HXT3, HXT13, HXT10, MAL11, HXT4, HXT1, HXT5, HXT8, HXT9, HXT16, MPH3, GAL2, HXT2, HXT14, HXT17, HXT11
Phenotype(s): Viable
, Conditionally inviable when on glucose medium
The complete hxt null strain (EBY4000) is unable to take up hexoses and to grow on them. It is well suited to express and characterize heterologous glucose transporters. [4] [5]
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References
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- ↑ Andre B (1995) An overview of membrane transport proteins in Saccharomyces cerevisiae. Yeast 11(16):1575-611 SGD PMID 8720066
- ↑ Kruckeberg AL (1996) The hexose transporter family of Saccharomyces cerevisiae. Arch Microbiol 166(5):283-92 SGD PMID 8929273
- ↑ Nelissen B, et al. (1995) Phylogenetic classification of the major superfamily of membrane transport facilitators, as deduced from yeast genome sequencing. FEBS Lett 377(2):232-6 SGD PMID 8543057
- ↑ 4.0 4.1 Wieczorke R, et al. (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8
SGD PMID 10618490 Cite error: Invalid
<ref>tag; name "S000056317" defined multiple times with different content - ↑ submitted by Eckhard Boles on 2003-03-17
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