YIL125W

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Systematic name YIL125W
Gene name KGD1
Aliases OGD1
Feature type ORF, Verified
Coordinates Chr IX:122689..125733
Primary SGDID S000001387


Description of YIL125W: Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA[1]




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Protein Details

Other Protein Details

Other Topic: Regulated by the diauxic shift (glycerol)

Apart form the overall increase in mitochondrial protein mass after the diauxic shift this protein remains unchanged after the diauxic shift. [2] [3]





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References

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  1. Repetto B and Tzagoloff A (1989) Structure and regulation of KGD1, the structural gene for yeast alpha-ketoglutarate dehydrogenase. Mol Cell Biol 9(6):2695-705 SGD PMID 2503710
  2. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  3. submitted by Steffen Ohlmeier on 2004-04-08

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