YIL117C

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Systematic name YIL117C
Gene name PRM5
Aliases
Feature type ORF, Verified
Coordinates Chr IX:141569..140613
Primary SGDID S000001379


Description of YIL117C: Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling[1][2]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [3] [4]


Transmembrane Domain GxxxG

The transmembrane domain of Prm5p shows homology with the SKG6/AXL2 alpha-helix transmembrane domain (IPR014805). In particular, this domain begins with GgiaG. The presence of a GxxxG motif [5] strongly indicates that Prm5p dimerises.




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References

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  1. Heiman MG and Walter P (2000) Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating. J Cell Biol 151(3):719-30 SGD PMID 11062271
  2. Jung US and Levin DE (1999) Genome-wide analysis of gene expression regulated by the yeast cell wall integrity signalling pathway. Mol Microbiol 34(5):1049-57 SGD PMID 10594829
  3. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  4. submitted by Viktor Boer on 2003-07-25
  5. Senes A, Engel DE and DeGrado WF (2004) Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs. Curr Opin Struct Biol. 2004 14(4):465-79. PMID 15313242

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