YIL116W

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Systematic name YIL116W
Gene name HIS5
Aliases
Feature type ORF, Verified
Coordinates Chr IX:142928..144085
Primary SGDID S000001378


Description of YIL116W: Histidinol-phosphate aminotransferase, catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts[1][2][3][4]




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References

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  1. Alifano P, et al. (1996) Histidine biosynthetic pathway and genes: structure, regulation, and evolution. Microbiol Rev 60(1):44-69 SGD PMID 8852895
  2. Fink GR (1964) GENE-ENZYME RELATIONS IN HISTIDINE BIOSYNTHESIS IN YEAST. Science 146(3643):525-7 SGD PMID 14190241
  3. Harashima S, et al. (1981) Cloning of the HIS5 gene of Saccharomyces cerevisiae by yeast transformation. Gene 16(1-3):335-41 SGD PMID 7044894
  4. Pearce DA and Sherman F (1999) Toxicity of copper, cobalt, and nickel salts is dependent on histidine metabolism in the yeast Saccharomyces cerevisiae. J Bacteriol 181(16):4774-9 SGD PMID 10438744

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