YIL022W
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| Systematic name | YIL022W |
| Gene name | TIM44 |
| Aliases | ISP45, MIM44, MPI1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:311165..312460 |
| Primary SGDID | S000001284 |
Description of YIL022W: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); tethers the import motor and regulatory factors (PAM complex) to the translocation channel (Tim23p-Tim17p core complex)[1][2][3]
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References
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- ↑ D'Silva P, et al. (2004) Regulated interactions of mtHsp70 with Tim44 at the translocon in the mitochondrial inner membrane. Nat Struct Mol Biol 11(11):1084-91 SGD PMID 15489862
- ↑ Geissler A, et al. (2000) Biogenesis of the yeast frataxin homolog Yfh1p. Tim44-dependent transfer to mtHsp70 facilitates folding of newly imported proteins in mitochondria. Eur J Biochem 267(11):3167-80 SGD PMID 10824101
- ↑ Voos W, et al. (1996) Differential requirement for the mitochondrial Hsp70-Tim44 complex in unfolding and translocation of preproteins. EMBO J 15(11):2668-77 SGD PMID 8654364
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