YHR083W

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Systematic name YHR083W
Gene name SAM35
Aliases FMP20, TOB38, TOM38
Feature type ORF, Verified
Coordinates Chr VIII:272627..273616
Primary SGDID S000001125


Description of YHR083W: Essential component of the sorting and assembly machinery (SAM complex or TOB complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their insertion into the outer membrane[1][2][3][4]




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References

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  1. Habib SJ, et al. (2005) Assembly of the TOB complex of mitochondria. J Biol Chem 280(8):6434-40 SGD PMID 15590639
  2. Ishikawa D, et al. (2004) Two novel proteins in the mitochondrial outer membrane mediate beta-barrel protein assembly. J Cell Biol 166(5):621-7 SGD PMID 15326197
  3. Milenkovic D, et al. (2004) Sam35 of the mitochondrial protein sorting and assembly machinery is a peripheral outer membrane protein essential for cell viability. J Biol Chem 279(21):22781-5 SGD PMID 15067005
  4. Waizenegger T, et al. (2004) Tob38, a novel essential component in the biogenesis of beta-barrel proteins of mitochondria. EMBO Rep 5(7):704-9 SGD PMID 15205677

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