YHL043W

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Systematic name YHL043W
Gene name ECM34
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:14901..15413
Primary SGDID S000001035


Description of YHL043W: Putative protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins[1]




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Community Commentary

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DNA and RNA Details

Other DNA and RNA Details

Other Topic: evolution

The SSU1-R allele, which confers sulfite resistance to yeast cells, is the product of a reciprocal translocation between chromosomes VIII and XVI due to unequal crossing-over mediated by microhomology between very short sequences on the 5' upstream regions of the SSU1 and ECM34 genes. We show that this translocation is only present in wine yeast strains, suggesting that the use for millennia of sulfite as a preservative in wine production could have favoured its selection. [2] [3]





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References

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  1. Despons L, et al. (2006) An evolutionary scenario for one of the largest yeast gene families. Trends Genet 22(1):10-5 SGD PMID 16269202
  2. Perez-Ortin JE, et al. (2002) Molecular characterization of a chromosomal rearrangement involved in the adaptive evolution of yeast strains. Genome Res 12(10):1533-9 SGD PMID 12368245
  3. submitted by Jose E. Perez-Ortin on 2004-06-04

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