YHL002W

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Systematic name YHL002W
Gene name HSE1
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:102612..103970
Primary SGDID S000000994


Description of YHL002W: Subunit of the endosomal Vps27p-Hse1p complex required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes[1][2]




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References

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  1. Bilodeau PS, et al. (2002) The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting. Nat Cell Biol 4(7):534-9 SGD PMID 12055639
  2. Bilodeau PS, et al. (2003) Vps27-Hse1 and ESCRT-I complexes cooperate to increase efficiency of sorting ubiquitinated proteins at the endosome. J Cell Biol 163(2):237-43 SGD PMID 14581452

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