YGR243W

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Systematic name YGR243W
Gene name FMP43
Aliases MPC3
Feature type ORF, Verified
Coordinates Chr VII:977336..977776
Primary SGDID S000003475


Description of YGR243W: Highly conserved subunit of the mitochondrial pyruvate carrier; a mitochondrial inner membrane complex comprised of Fmp37p/Mpc1p and either Mpc2p or Fmp43p/Mpc3p mediates mitochondrial pyruvate uptake; more highly expressed in glucose-containing minimal medium than in lactate-containing medium; expression regulated by osmotic and alkaline stresses[1][2][3][4][5][6]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [7] [8]





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References

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  1. Bricker DK, et al. (2012) A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila, and Humans. Science () SGD PMID 22628558
  2. Herzig S, et al. (2012) Identification and Functional Expression of the Mitochondrial Pyruvate Carrier. Science () SGD PMID 22628554
  3. Liu X, et al. (2007) Genetic and Comparative Transcriptome Analysis of Bromodomain Factor 1 in the Salt Stress Response of Saccharomyces cerevisiae. Curr Microbiol 54(4):325-30 SGD PMID 17334841
  4. Proft M, et al. (2005) Genomewide identification of Sko1 target promoters reveals a regulatory network that operates in response to osmotic stress in Saccharomyces cerevisiae. Eukaryot Cell 4(8):1343-52 SGD PMID 16087739
  5. Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 SGD PMID 16823961
  6. Viladevall L, et al. (2004) Characterization of the calcium-mediated response to alkaline stress in Saccharomyces cerevisiae. J Biol Chem 279(42):43614-24 SGD PMID 15299026
  7. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  8. submitted by Viktor Boer on 2003-07-25

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