YGR243W

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Systematic name YGR243W
Gene name FMP43
Aliases MPC3
Feature type ORF, Verified
Coordinates Chr VII:977336..977776
Primary SGDID S000003475


Description of YGR243W: Highly conserved subunit of the mitochondrial pyruvate carrier; a mitochondrial inner membrane complex comprised of Fmp37p/Mpc1p and either Mpc2p or Fmp43p/Mpc3p mediates mitochondrial pyruvate uptake; more highly expressed in glucose-containing minimal medium than in lactate-containing medium; expression regulated by osmotic and alkaline stresses[1][2][3][4][5][6]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [7] [8]





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References

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  1. ↑ Bricker DK, et al. (2012) A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila, and Humans. Science () SGD PMID 22628558
  2. ↑ Herzig S, et al. (2012) Identification and Functional Expression of the Mitochondrial Pyruvate Carrier. Science () SGD PMID 22628554
  3. ↑ Liu X, et al. (2007) Genetic and Comparative Transcriptome Analysis of Bromodomain Factor 1 in the Salt Stress Response of Saccharomyces cerevisiae. Curr Microbiol 54(4):325-30 SGD PMID 17334841
  4. ↑ Proft M, et al. (2005) Genomewide identification of Sko1 target promoters reveals a regulatory network that operates in response to osmotic stress in Saccharomyces cerevisiae. Eukaryot Cell 4(8):1343-52 SGD PMID 16087739
  5. ↑ Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 SGD PMID 16823961
  6. ↑ Viladevall L, et al. (2004) Characterization of the calcium-mediated response to alkaline stress in Saccharomyces cerevisiae. J Biol Chem 279(42):43614-24 SGD PMID 15299026
  7. ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  8. ↑ submitted by Viktor Boer on 2003-07-25

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