YGR224W

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Systematic name YGR224W
Gene name AZR1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:942806..944647
Primary SGDID S000003456


Description of YGR224W: Plasma membrane transporter of the major facilitator superfamily, involved in resistance to azole drugs such as ketoconazole and fluconazole[1][2]




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References

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  1. Bauer BE, et al. (2003) Weak organic acid stress inhibits aromatic amino acid uptake by yeast, causing a strong influence of amino acid auxotrophies on the phenotypes of membrane transporter mutants. Eur J Biochem 270(15):3189-95 SGD PMID 12869194
  2. Tenreiro S, et al. (2000) Expression of the AZR1 gene (ORF YGR224w), encoding a plasma membrane transporter of the major facilitator superfamily, is required for adaptation to acetic acid and resistance to azoles in Saccharomyces cerevisiae. Yeast 16(16):1469-81 SGD PMID 11113970

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