YGL212W

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Systematic name YGL212W
Gene name VAM7
Aliases VPL24, VPS43
Feature type ORF, Verified
Coordinates Chr VII:91432..92382
Primary SGDID S000003180


Description of YGL212W: Vacuolar SNARE protein that functions with Vam3p in vacuolar protein trafficking; has an N-terminal PX domain (phosphoinositide-binding module) that binds PtdIns-3-P and mediates membrane binding; SNAP-25 homolog[1][2][3]




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References

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  1. Sato TK, et al. (1998) Vam7p, a SNAP-25-like molecule, and Vam3p, a syntaxin homolog, function together in yeast vacuolar protein trafficking. Mol Cell Biol 18(9):5308-19 SGD PMID 9710615
  2. Ungermann C and Wickner W (1998) Vam7p, a vacuolar SNAP-25 homolog, is required for SNARE complex integrity and vacuole docking and fusion. EMBO J 17(12):3269-76 SGD PMID 9628864
  3. Yu JW and Lemmon MA (2001) All phox homology (PX) domains from Saccharomyces cerevisiae specifically recognize phosphatidylinositol 3-phosphate. J Biol Chem 276(47):44179-84 SGD PMID 11557775

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