YGL191W

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Systematic name YGL191W
Gene name COX13
Aliases
Feature type ORF, Verified
Coordinates Chr VII:144808..145197
Primary SGDID S000003159


Description of YGL191W: Subunit VIa of cytochrome c oxidase; present in a subclass of cytochrome c oxidase complexes that may have a role in mimimizing generation of reactive oxygen species; not essential for cytochrome c oxidase activity but may modulate activity in response to ATP; required for assembly of Rcf2p into cytochrome c oxidase - cytochrome bc1 supercomplexes[1][2]




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Protein Details

Other Protein Details

Other Topic: Regulated by the diauxic shift (glycerol)

Apart form the overall increase in mitochondrial protein mass after the diauxic shift this protein remains unchanged after the diauxic shift. [3] [4]





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References

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  1. ↑ Taanman JW and Capaldi RA (1993) Subunit VIa of yeast cytochrome c oxidase is not necessary for assembly of the enzyme complex but modulates the enzyme activity. Isolation and characterization of the nuclear-coded gene. J Biol Chem 268(25):18754-61 SGD PMID 8395517
  2. ↑ Vukotic M, et al. (2012) Rcf1 Mediates Cytochrome Oxidase Assembly and Respirasome Formation, Revealing Heterogeneity of the Enzyme Complex. Cell Metab () SGD PMID 22342701
  3. ↑ Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  4. ↑ submitted by Steffen Ohlmeier on 2004-04-08

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