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Systematic name YGL124C
Gene name MON1
Aliases AUT12
Feature type ORF, Verified
Coordinates Chr VII:276714..274780
Primary SGDID S000003092

Description of YGL124C: Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a complex with Ccz1p, with a perivacuolar compartment; potential Cdc28p substrate[1][2]


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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]



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  1. Meiling-Wesse K, et al. (2002) Yeast Mon1p/Aut12p functions in vacuolar fusion of autophagosomes and cvt-vesicles. FEBS Lett 530(1-3):174-80 SGD PMID 12387888
  2. Wang CW, et al. (2002) The Ccz1-Mon1 protein complex is required for the late step of multiple vacuole delivery pathways. J Biol Chem 277(49):47917-27 SGD PMID 12364329
  3. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. submitted by Jeff Ubersax on 2004-01-27

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