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Systematic name YGL123W
Gene name RPS2
Aliases RPS4, SUP138, SUP38, SUP44
Feature type ORF, Verified
Coordinates Chr VII:277617..278381
Primary SGDID S000003091

Description of YGL123W: Protein component of the small (40S) subunit; essential for control of translational accuracy; phosphorylation by C-terminal domain kinase I (CTDK-I) enhances translational accuracy; methylated on one or more arginine residues by Hmt1p; homologous to mammalian ribosomal protein S2 and bacterial S5[1][2][3][4]


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  1. Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol () SGD PMID 22884264
  2. Lipson RS, et al. (2010) Rmt1 catalyzes zinc-finger independent arginine methylation of ribosomal protein Rps2 in Saccharomyces cerevisiae. Biochem Biophys Res Commun 391(4):1658-62 SGD PMID 20035717
  3. Rother S and Strasser K (2007) The RNA polymerase II CTD kinase Ctk1 functions in translation elongation. Genes Dev 21(11):1409-21 SGD PMID 17545469
  4. Synetos D, et al. (1996) Mutations in yeast ribosomal proteins S28 and S4 affect the accuracy of translation and alter the sensitivity of the ribosomes to paromomycin. Biochim Biophys Acta 1309(1-2):156-66 SGD PMID 8950190

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