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Systematic name YGL085W
Gene name LCL3
Feature type ORF, Uncharacterized
Coordinates Chr VII:349616..350440
Primary SGDID S000003053

Description of YGL085W: Putative protein of unknown function; mutant has long chronological lifespan; has homology to Staphylococcus aureus nuclease; GFP-fusion protein localizes to mitochondria; is induced in response to the DNA-damaging agent MMS[1][2][3][4]


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  1. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  2. Lee MW, et al. (2007) Global protein expression profiling of budding yeast in response to DNA damage. Yeast 24(3):145-54 SGD PMID 17351896
  3. Matecic M, et al. (2010) A microarray-based genetic screen for yeast chronological aging factors. PLoS Genet 6(4):e1000921 SGD PMID 20421943
  4. Ponting CP (1997) P100, a transcriptional coactivator, is a human homologue of staphylococcal nuclease. Protein Sci 6(2):459-63 SGD PMID 9041650

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