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Systematic name YGL073W
Gene name HSF1
Aliases EXA3, MAS3
Feature type ORF, Verified
Coordinates Chr VII:368753..371254
Primary SGDID S000003041

Description of YGL073W: Trimeric heat shock transcription factor, activates multiple genes in response to stresses that include hyperthermia; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; posttranslationally regulated[1][2][3][4]


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  1. Bonner JJ, et al. (2000) Structural analysis of yeast HSF by site-specific crosslinking. J Mol Biol 302(3):581-92 SGD PMID 10986120
  2. Bulman AL, et al. (2001) The DNA-binding domain of yeast heat shock transcription factor independently regulates both the N- and C-terminal activation domains. J Biol Chem 276(43):40254-62 SGD PMID 11509572
  3. Hoj A and Jakobsen BK (1994) A short element required for turning off heat shock transcription factor: evidence that phosphorylation enhances deactivation. EMBO J 13(11):2617-24 SGD PMID 8013461
  4. Yamamoto A, et al. (2005) Identification of a novel class of target genes and a novel type of binding sequence of heat shock transcription factor in Saccharomyces cerevisiae. J Biol Chem 280(12):11911-9 SGD PMID 15647283

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