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Systematic name YGL048C
Gene name RPT6
Aliases CIM3, CRL3, SCB68, SUG1
Feature type ORF, Verified
Coordinates Chr VII:411286..410069
Primary SGDID S000003016

Description of YGL048C: One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle[1][2][3][4]


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  1. Glickman MH, et al. (1999) Functional analysis of the proteasome regulatory particle. Mol Biol Rep 26(1-2):21-8 SGD PMID 10363642
  2. Rubin DM, et al. (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19 SGD PMID 9724628
  3. Russell SJ, et al. (1999) Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J Biol Chem 274(31):21943-52 SGD PMID 10419517
  4. Xie Y and Varshavsky A (2000) Physical association of ubiquitin ligases and the 26S proteasome. Proc Natl Acad Sci U S A 97(6):2497-502 SGD PMID 10688918

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