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Systematic name YGL045W
Gene name RIM8
Aliases ART9, PAL3, YGL046W
Feature type ORF, Verified
Coordinates Chr VII:414102..415730
Primary SGDID S000003013

Description of YGL045W: Protein involved in proteolytic activation of Rim101p in response to alkaline pH; interacts with ESCRT-1 subunits Stp22p and Vps28p; essential for anaerobic growth; member of the arrestin-related trafficking adaptor family[1][2][3][4][5]


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  1. Herrador A, et al. (2010) Recruitment of the ESCRT machinery to a putative seven-transmembrane-domain receptor is mediated by an arrestin-related protein. Mol Cell Biol 30(4):897-907 SGD PMID 20028738
  2. Li W and Mitchell AP (1997) Proteolytic activation of Rim1p, a positive regulator of yeast sporulation and invasive growth. Genetics 145(1):63-73 SGD PMID 9017390
  3. Lin CH, et al. (2008) Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135(4):714-25 SGD PMID 18976803
  4. Snoek IS and Steensma HY (2006) Why does Kluyveromyces lactis not grow under anaerobic conditions? Comparison of essential anaerobic genes of Saccharomyces cerevisiae with the Kluyveromyces lactis genome. FEMS Yeast Res 6(3):393-403 SGD PMID 16630279
  5. Treton B, et al. (2000) Ambient pH signalling in ascomycetous yeasts involves homologues of the Aspergillus nidulans genes palF and paIH. Mol Gen Genet 263(3):505-13 SGD PMID 10821185

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