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Systematic name YGL033W
Gene name HOP2
Feature type ORF, Verified
Coordinates Chr VII:435625..436351
Primary SGDID S000003001

Description of YGL033W: Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair[1][2]


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  1. Leu JY, et al. (1998) The meiosis-specific Hop2 protein of S. cerevisiae ensures synapsis between homologous chromosomes. Cell 94(3):375-86 SGD PMID 9708739
  2. Tsubouchi H and Roeder GS (2002) The Mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair. Mol Cell Biol 22(9):3078-88 SGD PMID 11940665

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