YGL027C

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Systematic name YGL027C
Gene name CWH41
Aliases DER7, GLS1
Feature type ORF, Verified
Coordinates Chr VII:446143..443642
Primary SGDID S000002995


Description of YGL027C: Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein involved in assembly of cell wall beta 1,6 glucan and asparagine-linked protein glycosylation; also involved in ER protein quality control and sensing of ER stress[1][2][3][4]




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References

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  1. Hitt R and Wolf DH (2004) DER7, encoding alpha-glucosidase I is essential for degradation of malfolded glycoproteins of the endoplasmic reticulum. FEMS Yeast Res 4(8):815-20 SGD PMID 15450188
  2. Jiang B, et al. (1996) CWH41 encodes a novel endoplasmic reticulum membrane N-glycoprotein involved in beta 1,6-glucan assembly. J Bacteriol 178(4):1162-71 SGD PMID 8576053
  3. Ram AF, et al. (1994) A new approach for isolating cell wall mutants in Saccharomyces cerevisiae by screening for hypersensitivity to calcofluor white. Yeast 10(8):1019-30 SGD PMID 7992502
  4. Romero PA, et al. (1997) The yeast CWH41 gene encodes glucosidase I. Glycobiology 7(7):997-1004 SGD PMID 9363442

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