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Systematic name YGL013C
Gene name PDR1
Aliases AMY1, ANT1, BOR2, CYH3, NRA2, SMR2, TIL1, TPE1, TPE3
Feature type ORF, Verified
Coordinates Chr VII:472298..469092
Primary SGDID S000002981

Description of YGL013C: Transcription factor that regulates the pleiotropic drug response; zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes; PDR1 has a paralog, PDR3, that arose from the whole genome duplication[1][2]


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  1. Akache B, et al. (2004) Complex interplay among regulators of drug resistance genes in Saccharomyces cerevisiae. J Biol Chem 279(27):27855-60 SGD PMID 15123673
  2. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922

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