YFR004W
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| Systematic name | YFR004W |
| Gene name | RPN11 |
| Aliases | MPR1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VI:153393..154313 |
| Primary SGDID | S000001900 |
Description of YFR004W: Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates; involved, independent of catalytic activity, in fission of mitochondria and peroxisomes[1][2][3][4]
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References
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- ↑ Berndt C, et al. (2002) Ubiquitin system: JAMMing in the name of the lid. Curr Biol 12(23):R815-7 SGD PMID 12477409
- ↑ Guterman A and Glickman MH (2004) Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome. J Biol Chem 279(3):1729-38 SGD PMID 14581483
- ↑ Hofmann L, et al. (2009) A nonproteolytic proteasome activity controls organelle fission in yeast. J Cell Sci 122(Pt 20):3673-83 SGD PMID 19773362
- ↑ Verma R, et al. (2002) Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome. Science 298(5593):611-5 SGD PMID 12183636
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