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Systematic name YFL017C
Gene name GNA1
Aliases PAT1
Feature type ORF, Verified
Coordinates Chr VI:104462..103983
Primary SGDID S000001877

Description of YFL017C: Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START, DNA synthesis, and mitosis; involved in UDP-N-acetylglucosamine synthesis, forms GlcNAc6P from AcCoA[1][2][3]


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  1. Lin R, et al. (1996) PAT1, an evolutionarily conserved acetyltransferase homologue, is required for multiple steps in the cell cycle. Genes Cells 1(10):923-42 SGD PMID 9077451
  2. Mio T, et al. (1999) Saccharomyces cerevisiae GNA1, an essential gene encoding a novel acetyltransferase involved in UDP-N-acetylglucosamine synthesis. J Biol Chem 274(1):424-9 SGD PMID 9867860
  3. Peneff C, et al. (2001) The crystal structures of Apo and complexed Saccharomyces cerevisiae GNA1 shed light on the catalytic mechanism of an amino-sugar N-acetyltransferase. J Biol Chem 276(19):16328-34 SGD PMID 11278591

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