YER190W

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Systematic name YER190W
Gene name YRF1-2
Aliases YRF1
Feature type ORF, Verified
Coordinates Chr V:571480..576525
Primary SGDID S000000992


Description of YER190W: Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; induced by treatment with 8-methoxypsoralen and UVA irradiation[1][2][3]




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References

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  1. Dardalhon M, et al. (2007) Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. FEMS Yeast Res 7(6):866-878 SGD PMID 17608707
  2. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  3. Yamada M, et al. (1998) Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. J Biol Chem 273(50):33360-6 SGD PMID 9837911

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