YER185W

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Systematic name YER185W
Gene name PUG1
Aliases
Feature type ORF, Verified
Coordinates Chr V:559454..560365
Primary SGDID S000000987


Description of YER185W: Plasma membrane protein with roles in the uptake of protoprophyrin IX and the efflux of heme; expression is induced under both low-heme and low-oxygen conditions; member of the fungal lipid-translocating exporter (LTE) family of proteins[1][2][3]




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References

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  1. Kim H, et al. (2003) Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions. J Biol Chem 278(12):10208-13 SGD PMID 12524434
  2. Manente M and Ghislain M (2009) The lipid-translocating exporter family and membrane phospholipid homeostasis in yeast. FEMS Yeast Res 9(5):673-87 SGD PMID 19416366
  3. Protchenko O, et al. (2008) Role of PUG1 in inducible porphyrin and heme transport in Saccharomyces cerevisiae. Eukaryot Cell 7(5):859-71 SGD PMID 18326586

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