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Systematic name YER176W
Gene name ECM32
Aliases HEL1, MTT1
Feature type ORF, Verified
Coordinates Chr V:541690..545055
Primary SGDID S000000978

Description of YER176W: DNA dependent ATPase/DNA helicase belonging to the Dna2p- and Nam7p-like family of helicases that is involved in modulating translation termination; interacts with the translation termination factors, localized to polysomes[1][2][3]


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  1. Bean DW and Matson SW (1997) Identification of the gene encoding scHelI, a DNA helicase from Saccharomyces cerevisiae. Yeast 13(15):1465-75 SGD PMID 9434351
  2. Biswas EE, et al. (1995) Biochemical and genetic characterization of a replication protein A dependent DNA helicase from the yeast, Saccharomyces cerevisiae. Biochem Biophys Res Commun 206(3):850-6 SGD PMID 7832796
  3. Czaplinski K, et al. (2000) Mtt1 is a Upf1-like helicase that interacts with the translation termination factors and whose overexpression can modulate termination efficiency. RNA 6(5):730-43 SGD PMID 10836794

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