YER161C

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Systematic name YER161C
Gene name SPT2
Aliases EXA1, SIN1
Feature type ORF, Verified
Coordinates Chr V:500348..499347
Primary SGDID S000000963


Description of YER161C: Protein involved in negative regulation of transcription; required for RNA polyadenylation; exhibits regulated interactions with both histones and SWI-SNF components, has similarity to mammalian HMG1 proteins[1][2]




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References

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  1. Hershkovits G, et al. (2006) Recruitment of mRNA cleavage/polyadenylation machinery by the yeast chromatin protein Sin1p/Spt2p. Proc Natl Acad Sci U S A 103(26):9808-13 SGD PMID 16788068
  2. Perez-Martin J and Johnson AD (1998) The C-terminal domain of Sin1 interacts with the SWI-SNF complex in yeast. Mol Cell Biol 18(7):4157-64 SGD PMID 9632800

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