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Systematic name YER133W
Gene name GLC7
Aliases CID1, DIS2, DIS2S1, PP1
Feature type ORF, Verified
Coordinates Chr V:432495..433958
Primary SGDID S000000935

Description of YER133W: Type 1 serine/threonine protein phosphatase catalytic subunit, involved in many processes (eg: glycogen metabolism, sporulation, mitosis); accumulates at mating projections by interaction with Afr1p; interacts with many regulatory subunits[1][2][3][4]


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  1. Bharucha JP, et al. (2008) Saccharomyces cerevisiae Afr1 protein is a protein phosphatase 1/Glc7-targeting subunit that regulates the septin cytoskeleton during mating. Eukaryot Cell 7(8):1246-55 SGD PMID 18552279
  2. Feng ZH, et al. (1991) The yeast GLC7 gene required for glycogen accumulation encodes a type 1 protein phosphatase. J Biol Chem 266(35):23796-801 SGD PMID 1660885
  3. Nigavekar SS, et al. (2002) Glc8 is a glucose-repressible activator of Glc7 protein phosphatase-1. Arch Biochem Biophys 404(1):71-9 SGD PMID 12127071
  4. Stark MJ (1996) Yeast protein serine/threonine phosphatases: multiple roles and diverse regulation. Yeast 12(16):1647-75 SGD PMID 9123967

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