YER052C

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Systematic name YER052C
Gene name HOM3
Aliases BOR1, SIL4, THR3
Feature type ORF, Verified
Coordinates Chr V:257958..256375
Primary SGDID S000000854


Description of YER052C: Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis[1][2][3][4]




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References

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  1. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  2. Jones EW and Fink GR (1982) Regulation of amino acid and nucleotide biosynthesis in yeast. Pp.181-299 in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, edited by Strathern JN, Jones EW and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press SGD PMID
  3. Mountain HA, et al. (1991) Four major transcriptional responses in the methionine/threonine biosynthetic pathway of Saccharomyces cerevisiae. Yeast 7(8):781-803 SGD PMID 1789001
  4. Rafalski JA and Falco SC (1988) Structure of the yeast HOM3 gene which encodes aspartokinase. J Biol Chem 263(5):2146-51 SGD PMID 2892836

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