YEL027W

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Systematic name YEL027W
Gene name VMA3
Aliases CLS7, CUP5, GEF2
Feature type ORF, Verified
Coordinates Chr V:100769..101251
Primary SGDID S000000753


Description of YEL027W: Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohexylcarbodiimide binding subunit); required for vacuolar acidification and important for copper and iron metal ion homeostasis[1][2]




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References

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  1. Eide DJ, et al. (1993) The vacuolar H(+)-ATPase of Saccharomyces cerevisiae is required for efficient copper detoxification, mitochondrial function, and iron metabolism. Mol Gen Genet 241(3-4):447-56 SGD PMID 8246899
  2. Szczypka MS, et al. (1997) Saccharomyces cerevisiae mutants altered in vacuole function are defective in copper detoxification and iron-responsive gene transcription. Yeast 13(15):1423-35 SGD PMID 9434348

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