YDR507C

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Systematic name YDR507C
Gene name GIN4
Aliases ERC47
Feature type ORF, Verified
Coordinates Chr IV:1465786..1462358
Primary SGDID S000002915


Description of YDR507C: Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication[1][2][3][4]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]





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References

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  1. Altman R and Kellogg D (1997) Control of mitotic events by Nap1 and the Gin4 kinase. J Cell Biol 138(1):119-30 SGD PMID 9214386
  2. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  3. Iwase M and Toh-e A (2004) Ybr267w is a new cytoplasmic protein belonging to the mitotic signaling network of Saccharomyces cerevisiae. Cell Struct Funct 29(1):1-15 SGD PMID 15107529
  4. Okuzaki D, et al. (2003) The Saccharomyces cerevisiae bud-neck proteins Kcc4 and Gin4 have distinct but partially-overlapping cellular functions. Genes Genet Syst 78(2):113-26 SGD PMID 12773812
  5. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  6. submitted by Jeff Ubersax on 2004-01-27

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