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Systematic name YDR485C
Gene name VPS72
Aliases SWC2
Feature type ORF, Verified
Coordinates Chr IV:1427207..1424820
Primary SGDID S000002893

Description of YDR485C: Htz1p-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting[1][2]


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  1. Bonangelino CJ, et al. (2002) Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Mol Biol Cell 13(7):2486-501 SGD PMID 12134085
  2. Wu WH, et al. (2005) Swc2 is a widely conserved H2AZ-binding module essential for ATP-dependent histone exchange. Nat Struct Mol Biol 12(12):1064-71 SGD PMID 16299513

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