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Systematic name YDR459C
Gene name PFA5
Feature type ORF, Verified
Coordinates Chr IV:1383443..1382319
Primary SGDID S000002867

Description of YDR459C: Palmitoyltransferase with autoacylation activity; likely functions in pathway(s) outside Ras; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain[1][2][3][4]


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  1. Bartels DJ, et al. (1999) Erf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae. Mol Cell Biol 19(10):6775-87 SGD PMID 10490616
  2. Mitchell DA, et al. (2006) Protein palmitoylation by a family of DHHC protein S-acyltransferases. J Lipid Res 47(6):1118-27 SGD PMID 16582420
  3. Smotrys JE, et al. (2005) The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p. J Cell Biol 170(7):1091-9 SGD PMID 16186255
  4. Valdez-Taubas J and Pelham H (2005) Swf1-dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation. EMBO J 24(14):2524-32 SGD PMID 15973437

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