From SGD-Wiki
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YDR416W
Gene name SYF1
Aliases NTC90
Feature type ORF, Verified
Coordinates Chr IV:1298432..1301011
Primary SGDID S000002824

Description of YDR416W: Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; null mutant has splicing defect and arrests in G2/M; homologs in human and C. elegans[1][2][3]


Community Commentary

About Community Commentary. Please share your knowledge!



See Help:References on how to add references

  1. Ben-Yehuda S, et al. (2000) Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics 156(4):1503-17 SGD PMID 11102353
  2. Chen CH, et al. (2006) Functional links between the Prp19-associated complex, U4/U6 biogenesis, and spliceosome recycling. RNA 12(5):765-74 SGD PMID 16540691
  3. Russell CS, et al. (2000) Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae. RNA 6(11):1565-72 SGD PMID 11105756

See Help:Categories on how to add the wiki page for this gene to a Category </protect>