YDR324C

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Systematic name YDR324C
Gene name UTP4
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1116763..1114433
Primary SGDID S000002732


Description of YDR324C: Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; member of t-Utp subcomplex involved with transcription of 35S rRNA transcript[1][2][3][4]




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References

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  1. Dragon F, et al. (2002) A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 417(6892):967-70 SGD PMID 12068309
  2. Gallagher JE, et al. (2004) RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Genes Dev 18(20):2506-17 SGD PMID 15489292
  3. Grandi P, et al. (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15 SGD PMID 12150911
  4. Perez-Fernandez J, et al. (2007) The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol 27(15):5414-29 SGD PMID 17515605

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