YDR296W
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| Systematic name | YDR296W |
| Gene name | MHR1 |
| Aliases | XTC1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1055212..1055892 |
| Primary SGDID | S000002704 |
Description of YDR296W: Protein involved in homologous recombination in mitochondria; required for recombination-dependent mtDNA partitioning; involved in stimulation of mitochondrial DNA replication in response to oxidative stress[1][2][3][4]
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References
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- ↑ Hori A, et al. (2009) Reactive oxygen species regulate DNA copy number in isolated yeast mitochondria by triggering recombination-mediated replication. Nucleic Acids Res 37(3):749-61 SGD PMID 19074198
- ↑ Ling F and Shibata T (2002) Recombination-dependent mtDNA partitioning: in vivo role of Mhr1p to promote pairing of homologous DNA. EMBO J 21(17):4730-40 SGD PMID 12198175
- ↑ Ling F, et al. (2000) A role for MHR1, a gene required for mitochondrial genetic recombination, in the repair of damage spontaneously introduced in yeast mtDNA. Nucleic Acids Res 28(24):4956-63 SGD PMID 11121487
- ↑ Traven A, et al. (2002) The yeast protein Xtc1 functions as a direct transcriptional repressor. Nucleic Acids Res 30(11):2358-64 SGD PMID 12034822
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