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Systematic name YDR294C
Gene name DPL1
Aliases BST1
Feature type ORF, Verified
Coordinates Chr IV:1052228..1050459
Primary SGDID S000002702

Description of YDR294C: Dihydrosphingosine phosphate lyase, regulates intracellular levels of sphingolipid long-chain base phosphates (LCBPs), degrades phosphorylated long chain bases, prefers C16 dihydrosphingosine-l-phosphate as a substrate[1][2][3]


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  1. Grote E, et al. (2000) A snc1 endocytosis mutant: phenotypic analysis and suppression by overproduction of dihydrosphingosine phosphate lyase. Mol Biol Cell 11(12):4051-65 SGD PMID 11102507
  2. Kim S, et al. (2000) Accumulation of phosphorylated sphingoid long chain bases results in cell growth inhibition in Saccharomyces cerevisiae. Genetics 156(4):1519-29 SGD PMID 11102354
  3. Zhang X, et al. (2001) Elevation of endogenous sphingolipid long-chain base phosphates kills Saccharomyces cerevisiae cells. Curr Genet 40(4):221-33 SGD PMID 11795842

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