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Systematic name YDR151C
Gene name CTH1
Feature type ORF, Verified
Coordinates Chr IV:765155..764178
Primary SGDID S000002558

Description of YDR151C: Member of the CCCH zinc finger family; has similarity to mammalian Tis11 protein, which activates transcription and also has a role in mRNA degradation; may function with Tis11p in iron homeostasis[1][2][3]


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  1. Puig S, et al. (2005) Coordinated remodeling of cellular metabolism during iron deficiency through targeted mRNA degradation. Cell 120(1):99-110 SGD PMID 15652485
  2. Thompson MJ, et al. (1996) Cloning and characterization of two yeast genes encoding members of the CCCH class of zinc finger proteins: zinc finger-mediated impairment of cell growth. Gene 174(2):225-33 SGD PMID 8890739
  3. Wu X, et al. (2000) The Ess1 prolyl isomerase is linked to chromatin remodeling complexes and the general transcription machinery. EMBO J 19(14):3727-38 SGD PMID 10899126

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