YDR144C

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Systematic name YDR144C
Gene name MKC7
Aliases YPS2
Feature type ORF, Verified
Coordinates Chr IV:746101..744311
Primary SGDID S000002551


Description of YDR144C: GPI-anchored aspartyl protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; shares functions with Yap3p and Kex2p[1][2][3]




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References

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  1. Komano H and Fuller RS (1995) Shared functions in vivo of a glycosyl-phosphatidylinositol-linked aspartyl protease, Mkc7, and the proprotein processing protease Kex2 in yeast. Proc Natl Acad Sci U S A 92(23):10752-6 SGD PMID 7479877
  2. Komano H, et al. (1999) Purification and characterization of the yeast glycosylphosphatidylinositol-anchored, monobasic-specific aspartyl protease yapsin 2 (Mkc7p). J Biol Chem 274(34):24431-7 SGD PMID 10446224
  3. Krysan DJ, et al. (2005) Yapsins are a family of aspartyl proteases required for cell wall integrity in Saccharomyces cerevisiae. Eukaryot Cell 4(8):1364-74 SGD PMID 16087741

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